Description

2-Amino-3,5-Difluorobenzoic Acid is a high-purity fluorinated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and an amino group on the aromatic ring, enabling precise modulation of electronic properties, lipophilicity, and metabolic stability in target molecules. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced performance profiles.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoro-amino-benzoate structure contributes to biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and organic electronic materials to alter dielectric properties and stability.
• Fluorescent Probe and Dye Chemistry: Acts as a building block for synthesizing fluorophores and molecular probes used in bioimaging and diagnostic assays.

Basic Information

Product Name	2-Amino-3,5-Difluorobenzoic Acid
CAS No.	126674-78-0
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	3,5-Difluoro-2-aminobenzoic Acid; 2-Amino-3,5-difluorobenzoic Acid; Benzoic acid, 2-amino-3,5-difluoro-; 3,5-Difluoroanthranilic Acid
EINECS	Contact for details

Quality Control

Our 2-Amino-3,5-Difluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. The compound is light-sensitive; prolonged exposure should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	205 - 210 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.