Description

1-(3-Cytosinyl)-2-(1-Guanyl)Ethane CAS NO 126175-83-5 is a high-purity, modified nucleoside derivative of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and molecular probe for studying nucleic acid interactions, enzyme mechanisms, and cellular processes. It is essential for researchers and manufacturers in the fields of nucleic acid chemistry, antiviral drug discovery, and molecular diagnostics, where precise and reliable chemical tools are paramount.

Application

• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving DNA/RNA polymerases, nucleotidyltransferases, and repair enzymes.
• Antiviral & Anticancer Agent Development: Serves as a key synthetic intermediate or analog in the design and synthesis of novel nucleoside-based therapeutics targeting viral replication and cancer cell proliferation.
• Molecular Probe Synthesis: Incorporated into oligonucleotides to create labeled probes for studying DNA-protein interactions, gene expression analysis, and diagnostic assay development.
• Nucleic Acid Chemistry: Employed in the synthesis of modified oligonucleotides to investigate structure-function relationships and enhance stability or binding affinity.
• Academic & Pharmaceutical R&D: A vital reagent for basic research in universities and for drug discovery pipelines in pharmaceutical companies, supporting innovation in life sciences.

Basic Information

Item	Detail
Product Name	1-(3-Cytosinyl)-2-(1-Guanyl)Ethane
CAS No.	126175-83-5
Molecular Formula	C11H14N8O3
Molecular Weight	306.28 g/mol
Synonyms	1-(3-Cytosinyl)-2-(1-guanyl)ethane; 1-(N3-Cytosinyl)-2-(N1-guanyl)ethane; Cytosinyl-guanyl ethane crosslink; C-G Ethane Cross-link; DNA Interstrand Cross-link Model Compound; 1,2-Ethanediylbis(cytosine-guanine); Nucleoside Cross-link Derivative
EINECS	Contact for details

Quality Control

Our 1-(3-Cytosinyl)-2-(1-Guanyl)Ethane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.