Description

Methyl 5-Amino-2,4-Difluorobenzoate is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique combination of an amino group and fluorine substituents, which are critical for modulating the biological activity and physicochemical properties of target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the difluoro and amino groups contribute to efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated compounds used in electronic displays and organic light-emitting diodes (OLEDs).
• Advanced Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and specialty chemicals with tailored properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	Methyl 5-Amino-2,4-Difluorobenzoate
CAS No.	125568-73-2
Molecular Formula	C8H7F2NO2
Molecular Weight	187.14 g/mol
Synonyms	5-Amino-2,4-difluorobenzoic acid methyl ester; Methyl 5-amino-2,4-difluorobenzoate; Benzoic acid, 5-amino-2,4-difluoro-, methyl ester; 2,4-Difluoro-5-aminobenzoic acid methyl ester; Methyl 2,4-difluoro-5-aminobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 5-Amino-2,4-Difluorobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry standards. Custom purity grades, including research and GMP grades, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, prolonged storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.