Description

2,4-Difluoro-5-Nitrobenzoic Acid Methyl Ester is a high-value fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring both nitro and fluorine substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a building block for creating fluorescent probes, enzyme inhibitors, and other molecular tools for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2,4-Difluoro-5-Nitrobenzoic Acid Methyl Ester
CAS No.	125568-71-0
Molecular Formula	C8H5F2NO4
Molecular Weight	217.13 g/mol
Synonyms	Methyl 2,4-difluoro-5-nitrobenzoate; 5-Nitro-2,4-difluorobenzoic Acid Methyl Ester; Benzoic acid, 2,4-difluoro-5-nitro-, methyl ester; Methyl 5-nitro-2,4-difluorobenzoate; 2,4-Difluoro-5-nitro-benzoic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluoro-5-Nitrobenzoic Acid Methyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.