Description

2,4,5-Trifluoro-n-(1-Hydroxy-2-Methylpropan-2-Yl)Benzamide is a high-purity fluorinated benzamide derivative, a key building block in advanced organic synthesis. This compound matters for its role as a sophisticated intermediate in the development of complex molecules, particularly in the pharmaceutical sector where its trifluoromethyl and hydroxyl-bearing side chain offer valuable synthetic handles. It is primarily needed by R&D chemists and process development scientists in pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a fluorinated aromatic core.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of advanced polymers and liquid crystals, where its structure can influence material properties.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research focused on introducing fluorine into complex molecular architectures.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule construction and scale-up projects.

Basic Information

Product Name	2,4,5-Trifluoro-n-(1-Hydroxy-2-Methylpropan-2-Yl)Benzamide
CAS No.	125290-71-3
Molecular Formula	C11H11F3NO2
Molecular Weight	246.21 g/mol
Synonyms	2,4,5-Trifluoro-N-(1-hydroxy-2-methylpropan-2-yl)benzamide; 2,4,5-Trifluoro-N-(2-hydroxy-1,1-dimethylethyl)benzamide; Benzamide, 2,4,5-trifluoro-N-(1-hydroxy-2-methyl-2-propanyl)-; 2,4,5-Trifluoro-N-(2-hydroxy-2-methylpropyl)benzamide; 2,4,5-Trifluoro-N-(1-hydroxy-2-methyl-2-propyl)benzamide; 2,4,5-Trifluoro-N-(2-hydroxy-1,1-dimethylethyl)benzamide; N-(1-Hydroxy-2-methylpropan-2-yl)-2,4,5-trifluorobenzamide
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluoro-n-(1-Hydroxy-2-Methylpropan-2-Yl)Benzamide is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.