Description

5-(1-Cyano-4-((2-(5-Fluoro-2-Methoxyphenoxy)Ethyl)Amino)-1-Isopropylbutyl)-2-Methoxybenzenesulfonamide is a high-purity, complex organic intermediate with significant value in advanced pharmaceutical synthesis. This compound is critical for research and development teams working on novel therapeutic agents, particularly in specialized drug discovery pipelines. Its precise molecular architecture makes it an essential building block for medicinal chemists in the pharmaceutical and biotechnology sectors targeting specific biological pathways.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies in drug discovery programs.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific enzyme or receptor interactions.
• Process Chemistry Development: Utilized for scaling up and optimizing synthetic routes for potential candidate drugs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and pharmacological research projects.

Basic Information

Product Name	5-(1-Cyano-4-((2-(5-Fluoro-2-Methoxyphenoxy)Ethyl)Amino)-1-Isopropylbutyl)-2-Methoxybenzenesulfonamide
CAS No.	125153-61-9
Molecular Formula	C24H32FN3O5S
Molecular Weight	493.60 g/mol
Synonyms	5-(1-Cyano-4-{[2-(5-Fluoro-2-methoxyphenoxy)ethyl]amino}-1-isopropylbutyl)-2-methoxybenzenesulfonamide; Benzenesulfonamide, 5-(1-cyano-4-((2-(5-fluoro-2-methoxyphenoxy)ethyl)amino)-1-(1-methylethyl)butyl)-2-methoxy-; TAK-044 Intermediate; Potential Endothelin Receptor Antagonist Intermediate; 125153-61-9; UNII-8V8T6Q5V6I; 8V8T6Q5V6I
EINECS	Contact for details

Quality Control

Our 5-(1-Cyano-4-((2-(5-Fluoro-2-Methoxyphenoxy)Ethyl)Amino)-1-Isopropylbutyl)-2-Methoxybenzenesulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.