Description

n-[(3S,4R)-1-(2-Ethoxyethyl)-3-Methyl-4-Piperidyl]-n-Phenyl-Acetamide is a high-purity, stereochemically defined piperidine derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated chiral building block, enabling the development of novel molecules with precise three-dimensional structures. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of potential active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and development of new therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Chemical Research: Acts as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex, chirally pure molecules.
• Reference Standard: Utilized as an analytical standard for method development and quality control in chiral analysis.

Basic Information

Product Name	n-[(3S,4R)-1-(2-Ethoxyethyl)-3-Methyl-4-Piperidyl]-n-Phenyl-Acetamide
CAS No.	125080-87-7
Molecular Formula	C18H28N2O2
Molecular Weight	304.43 g/mol
Synonyms	N-[(3S,4R)-1-(2-Ethoxyethyl)-3-methyl-4-piperidinyl]-N-phenylacetamide; (3S,4R)-N-Phenyl-1-(2-ethoxyethyl)-3-methyl-4-piperidinamine N-acetate; 1-(2-Ethoxyethyl)-3-methyl-4-(N-phenylacetamido)piperidine; Acetamide, N-[(3S,4R)-1-(2-ethoxyethyl)-3-methyl-4-piperidinyl]-N-phenyl-; Stereoisomer of Fentanyl intermediate
EINECS	Contact for details

Quality Control

Our n-[(3S,4R)-1-(2-Ethoxyethyl)-3-Methyl-4-Piperidyl]-n-Phenyl-Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.