Description

2,3,4,5-Tetrahydro-5-Methyl-2-[(5-Methyl-1H-Imidazol-4-Yl)Methyl]- 1H-Pyrido[4,3-B]Indol-1-One (2Z)-2-Butenedioate is a high-purity, complex heterocyclic compound primarily utilized as a critical intermediate in advanced pharmaceutical synthesis. This compound matters because it provides a structurally defined building block essential for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and receptor-targeted drug discovery. It is specifically needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric targets.
• Biochemical Research: Used as a reference standard or ligand in receptor binding studies and pharmacological assays.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for API (Active Pharmaceutical Ingredient) manufacturing.
• Contract Research Organizations (CROs): Supplied to CROs engaged in custom synthesis and early-stage drug discovery projects.
• Academic Research: Utilized in university laboratories for studies in organic synthesis methodology and heterocyclic chemistry.

Basic Information

Product Name	2,3,4,5-Tetrahydro-5-Methyl-2-[(5-Methyl-1H-Imidazol-4-Yl)Methyl]- 1H-Pyrido[4,3-B]Indol-1-One (2Z)-2-Butenedioate
CAS No.	122852-43-1
Molecular Formula	C21H22N4O5
Molecular Weight	410.43 g/mol
Synonyms	5-Methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one (2Z)-2-butenedioate; Fumarate salt of the corresponding indole alkaloid derivative; Tetrahydro-β-carboline imidazole fumarate; Pyridoindole-imidazole fumarate; (2Z)-2-Butenedioic acid compound with 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one (1:1); Potential research code compound.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. We employ advanced analytical techniques including HPLC, NMR, and MS to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Our quality management system supports traceability and documentation suitable for cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.