Description

Methyl 4-Azido-2,3,5,6-Tetrafluorobenzoate is a high-value, multi-functional fluorinated aromatic building block, essential for advanced organic synthesis and materials science. Its unique structure, featuring both an azido group and a perfluorinated benzoate ester, makes it a critical precursor for click chemistry reactions and the development of novel fluorinated compounds. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries for creating complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and potential PET imaging agents via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry.
• Agrochemical Research: Used to introduce fluorine and azide functional groups into novel herbicide and pesticide candidates to enhance biological activity and metabolic stability.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for developing specialty fluoropolymers, surface coatings, and high-performance materials with unique chemical resistance and surface properties.
• Ligand & Catalyst Development: Employed in the preparation of novel fluorinated ligands and organocatalysts for asymmetric synthesis and catalysis research.
• Bioconjugation & Probe Synthesis: Facilitates the labeling and modification of biomolecules (proteins, peptides) for diagnostic assays and biochemical research due to its reactive azide group.
• Energetic Materials Research: Investigated as a component in the design of novel, high-density energetic materials and propellants.

Basic Information

Item	Detail
Product Name	Methyl 4-Azido-2,3,5,6-Tetrafluorobenzoate
CAS No.	122590-75-4
Molecular Formula	C8H3F4N3O2
Molecular Weight	249.12 g/mol
Synonyms	Methyl 4-azidotetrafluorobenzoate; 4-Azido-2,3,5,6-tetrafluorobenzoic Acid Methyl Ester; Benzoic acid, 4-azido-2,3,5,6-tetrafluoro-, methyl ester; Methyl perfluoro-4-azidobenzoate; Azidotetrafluoromethylbenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 4-Azido-2,3,5,6-Tetrafluorobenzoate adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of the azido functional group, it should be handled as a potential shock-sensitive material and stored separately from strong bases and reducing agents. Always refer to the Safety Data Sheet (SDS) for complete handling and storage instructions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.