Description

Naltriben Mesylate CAS NO 122517-78-6 is a selective delta opioid receptor (DOR) antagonist. This compound is a critical research tool in neuropharmacology, enabling the study of opioid receptor subtypes and their roles in pain modulation, addiction, and neurological disorders. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on central nervous system drug discovery and advanced pharmacological studies.

Application

• Neuropharmacological Research: A key tool for investigating the specific functions of delta opioid receptors in the brain and nervous system.
• Pain Mechanism Studies: Used to elucidate the role of DOR in pain pathways and to evaluate potential novel analgesics.
• Addiction Research: Employed in preclinical studies to understand opioid dependence and to screen for potential treatments for substance use disorders.
• Receptor Binding Assays: Serves as a reference standard in competitive binding experiments to characterize new chemical entities.
• Signal Transduction Studies: Helps in mapping intracellular signaling pathways activated or inhibited by delta opioid receptor engagement.
• Biomarker Development: Supports research aimed at discovering biomarkers related to opioid system dysregulation.

Basic Information

Product Name	Naltriben Mesylate
CAS No.	122517-78-6
Molecular Formula	C28H32N2O5S
Molecular Weight	508.63 g/mol
Synonyms	17-Cyclopropylmethyl-6,7-didehydro-4,5α-epoxy-3,14-dihydroxy-6,7:2',3'-indolomorphinan Mesylate; Naltriben Methanesulfonate; Naltrindole Benzoate Derivative; DOR Antagonist; 17-Cyclopropylmethyl-6,7-didehydro-4,5α-epoxy-3,14-dihydroxy-6,7-2',3'-indolomorphinan Methanesulfonate
EINECS	Contact for details

Quality Control

Our Naltriben Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed results for traceability and to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.