Description

3,4,5-Trifluorobenzoic Acid is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique trifluoromethyl-substituted benzoic acid structure makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate fluorine atoms to modulate the biological activity, metabolic stability, and lipophilicity of target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where fluorine substitution enhances efficacy and environmental profile.
• Liquid Crystal Materials (LCs): Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Polymer & Material Science: Acts as a monomer or modifier for engineering plastics and specialty polymers to improve chemical resistance and thermal stability.
• Organic Electronic Materials: Employed in the synthesis of electron-transport materials and semiconductors for OLEDs and OFETs.
• Chemical Research & Development: A versatile building block for medicinal chemistry, process chemistry, and exploring new fluorination methodologies in academic and industrial R&D labs.

Basic Information

Product Name	3,4,5-Trifluorobenzoic Acid
CAS No.	121602-93-5
Molecular Formula	C7H3F3O2
Molecular Weight	188.09 g/mol
Synonyms	Benzoic acid, 3,4,5-trifluoro-; 3,4,5-Trifluorobenzenecarboxylic acid; 3,4,5-Trifluorobenzoic acid; 3,4,5-Trifluoro benzoic acid; 3,4,5-Trifluoro-Benzoic Acid; 3,4,5-Trifluorophenylcarboxylic acid; 3,4,5-Trifluorobenzene-1-carboxylic acid; 3,4,5-Trifluoro-1-benzoic acid
EINECS	Contact for details

Quality Control

Our 3,4,5-Trifluorobenzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.