Description

Amesergide CAS NO 121588-75-8 is a high-purity chemical compound belonging to the ergoline class, known for its specific pharmacological activity. This compound is critical for research and development in the life sciences sector, where precise chemical structure and purity are paramount. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in developing and studying central nervous system (CNS) agents.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or reference standard in the synthesis and study of novel therapeutic agents targeting serotonin receptors.
• Neuropharmacology Studies: Used as a potent and selective 5-HT1A and 5-HT2 receptor antagonist in preclinical research to investigate neurological pathways and disorders.
• Biochemical Assay Development: Employed as a critical reagent in the development and validation of high-throughput screening (HTS) assays for drug discovery programs.
• Academic Research: Utilized in university and institutional labs for fundamental studies on neurotransmitter systems, receptor binding, and signal transduction mechanisms.
• Reference Standard Manufacturing: Supplied to analytical and quality control laboratories for use as a certified reference material (CRM) in method development and validation.
• Fine Chemical Synthesis: Acts as a sophisticated building block for the custom synthesis of more complex, target-specific molecules in contract research and manufacturing (CRAM) organizations.

Basic Information

Product Name	Amesergide
CAS No.	121588-75-8
Molecular Formula	C18H24N4O2
Molecular Weight	328.41 g/mol
Synonyms	8β-[(Methylthio)methyl]-6-methylergoline-1-carboxamide; 1-Carbamoyl-8β-[(methylthio)methyl]-6-methylergoline; Amesergide; (8β)-8-[(Methylthio)methyl]-6-methylergoline-1-carboxamide; LY53857; LY-53857
EINECS	Contact for details

Quality Control

Every batch of Amesergide is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with detailed Certificates of Analysis (COA) that include results from advanced techniques such as HPLC, NMR, and mass spectrometry. Our commitment to quality ensures the material meets the stringent requirements for pharmaceutical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.