Description

Ribonucleic Acid, Transfer is a specific class of RNA molecules essential for protein synthesis, functioning as adaptors that decode messenger RNA sequences into amino acids. This high-purity biochemical is critical for ensuring accuracy and efficiency in molecular biology research and biopharmaceutical development. It is primarily utilized by biotechnology companies, academic research institutions, and diagnostic manufacturers engaged in genetic studies, vaccine development, and therapeutic agent production.

Application

• Molecular Biology Research: Essential component for in vitro transcription/translation systems, tRNA charging assays, and studies of ribosomal function.
• Biopharmaceutical Development: Used in the research and production stages of mRNA-based vaccines and therapies, as well as in protein expression platforms.
• Diagnostic Kit Manufacturing: Serves as a key reagent or control in kits for genetic testing, pathogen detection, and metabolic disorder diagnosis.
• Enzymology Studies: Substrate for aminoacyl-tRNA synthetases and other RNA-modifying enzymes in mechanistic and kinetic studies.
• Structural Biology: Used in X-ray crystallography and cryo-electron microscopy to study the three-dimensional structure of ribosomes and translation complexes.
• Cell-Free Protein Synthesis: Critical for optimized cell-free systems used for rapid protein production and high-throughput screening.

Basic Information

Item	Details
Product Name	Ribonucleic Acid, Transfer
CAS No.	120991-81-3
Molecular Formula	Variable (RNA polymer)
Molecular Weight	Variable (typically 25,000 - 30,000 Da)
Synonyms	Transfer RNA; tRNA; Soluble RNA; sRNA; Amino Acid Acceptor RNA; 4S RNA; Adaptor RNA
EINECS	Contact for details

Quality Control

Our Ribonucleic Acid, Transfer is produced and tested under stringent quality management systems to ensure batch-to-batch consistency and reliability for critical research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and biological activity. We adhere to relevant guidelines for molecular biology-grade reagents, ensuring suitability for sensitive downstream applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to prevent condensation and moisture uptake. For extended storage, consider aliquoting to minimize freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 90% (tRNA)
Protein Content	≤ 1.0%
DNA Content	≤ 0.5%
Endotoxin	< 10 EU/mg
Biological Activity	Functional in in vitro translation assay
Solubility	Soluble in RNase-free water or buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.