Description

Mofegiline Hydrochloride is a selective and irreversible inhibitor of monoamine oxidase B (MAO-B), a key enzyme target in neurological research and development. This compound is valued for its high potency and specificity, making it a critical research chemical for investigating neurodegenerative pathways. It is primarily utilized by pharmaceutical R&D teams and academic institutions focused on developing novel therapeutic agents for conditions such as Parkinson's disease.

Application

• Pharmaceutical Research & Development (R&D): Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel MAO-B inhibitors for neurological disorders.
• Neuropharmacology Studies: Used in in vitro and in vivo studies to elucidate the role of MAO-B in dopamine metabolism and oxidative stress, relevant to Parkinson's disease models.
• Biochemical Assay Development: Employed as a potent inhibitor to validate enzyme activity assays and screen for new compounds targeting the MAO-B enzyme.
• Academic Research: A vital tool for universities and research institutes conducting fundamental neuroscience and medicinal chemistry research.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical products.

Basic Information

Product Name	Mofegiline Hydrochloride
CAS No.	120635-25-8
Molecular Formula	C13H19F2NO • HCl
Molecular Weight	263.75 g/mol (free base) / 300.21 g/mol (HCl salt)
Synonyms	MDL-72974A; (E)-2-(Fluoromethylene)-4-(4-fluorophenyl)butylamine hydrochloride; (E)-2-(Fluoromethylene)-4-(p-fluorophenyl)butylamine HCl; MDL 72974; p-[(E)-2-(Fluoromethylene)-4-aminobutyl]fluorobenzene hydrochloride; R-MDL 72974
EINECS	Contact for details

Quality Control

Our Mofegiline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and determination of residual solvents to ensure it meets high-purity standards suitable for research applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.