Description

1-Dodecanoyl-Sn-Glycerophosphoethanolamine is a synthetic, high-purity phospholipid derivative, specifically a lysophospholipid with a single lauroyl (C12:0) chain. This compound is a critical building block in lipid biochemistry and membrane research, offering precise structural control for creating model membranes and lipid-based delivery systems. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require defined lipid components for liposome formulation, drug delivery vehicles, and biomimetic studies.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: As a structural component for creating stable, uniform liposomes and LNPs for drug and gene delivery applications.
• Biomimetic Membrane Research: Used in the construction of supported lipid bilayers (SLBs) and giant unilamellar vesicles (GUVs) to study membrane properties, protein-lipid interactions, and cellular processes.
• Pharmaceutical Excipient: Serves as a functional excipient in advanced drug formulations to enhance stability, bioavailability, and targeted release.
• Biochemical Reagent: A key substrate or intermediate in enzymatic studies involving phospholipases and lipid metabolism pathways.
• Cosmetic & Dermal Delivery Systems: Incorporated into nanoemulsions and vesicles for improved skin penetration and delivery of active ingredients.
• Diagnostic Assay Development: Used to functionalize surfaces or create lipid environments in biosensors and diagnostic platforms.

Basic Information

Product Name	1-Dodecanoyl-Sn-Glycerophosphoethanolamine
CAS No.	120578-22-5
Molecular Formula	C17H36NO7P
Molecular Weight	397.44 g/mol
Synonyms	1-Lauroyl-2-hydroxy-sn-glycero-3-phosphoethanolamine; LysoPE(12:0/0:0); 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (common mis-association); LPE (12:0); 1-Dodecanoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine; Glycerophosphoethanolamine, 1-dodecanoyl-; sn-Glycero-3-phosphoethanolamine, 1-dodecanoyl derivative
EINECS	Contact for details

Quality Control

Our 1-Dodecanoyl-Sn-Glycerophosphoethanolamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research and cGMP-guided applications. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in chloroform, methanol; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.