Description

Cholesterylphosphoryldimethylethanolamine is a high-purity, synthetic phospholipid derivative, a key intermediate in advanced lipid research and formulation. This compound matters for its role in the development of novel liposomal drug delivery systems and biomimetic membrane models, enabling precise control over vesicle properties. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and specialty chemical manufacturers focused on targeted therapeutics and advanced biomaterials.

Application

• Liposomal Drug Delivery: A critical building block for synthesizing functionalized liposomes for targeted cancer therapy and gene delivery.
• Biomimetic Membrane Research: Used to create stable, cholesterol-rich model membranes for studying protein-lipid interactions and membrane dynamics.
• Pharmaceutical Intermediates: Serves as a key precursor in the synthesis of more complex, bioactive phospholipid conjugates.
• Diagnostic Reagent Formulation: Employed in the development of contrast agents and diagnostic kits requiring stable lipid assemblies.
• Cosmetic Actives Delivery: Enhances the encapsulation and skin penetration of active ingredients in high-end cosmetic formulations.
• Biochemical Research: A valuable tool for probing cholesterol trafficking and metabolism in cellular studies.

Basic Information

Product Name	Cholesterylphosphoryldimethylethanolamine
CAS No.	120087-00-5
Molecular Formula	C31H56NO4P
Molecular Weight	537.76 g/mol
Synonyms	Cholesteryl Dimethylphosphorylethanolamine; N,N-Dimethyl-2-aminoethyl Cholesteryl Hydrogen Phosphate; Chol-DMPE; Cholesterol Phosphoryldimethylethanolamine; 2-[[(3β)-Cholest-5-en-3-yloxy]-hydroxyphosphoryl]oxy]-N,N-dimethylethanaminium; Phosphorylcholine Cholesterol Derivative; (3β)-3-[[[2-(Dimethylamino)ethoxy]hydroxyphosphinyl]oxy]cholest-5-ene
EINECS	Contact for details

Quality Control

Our Cholesterylphosphoryldimethylethanolamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and pharmaceutical intermediate applications. Certificates of Analysis (COA) with full traceability are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.