Description

1-Stearoyl-2-Arachidonoylphosphatidic Acid is a defined, high-purity phospholipid species, a critical component for advanced biochemical and pharmaceutical research. This compound serves as a vital precursor and signaling molecule in the study of lipid metabolism, membrane dynamics, and cellular signaling pathways. It is essential for researchers and manufacturers in the fields of lipidomics, drug discovery, and the development of advanced lipid-based delivery systems such as liposomes and nanoparticles.

Application

• Biochemical Research: Used as a standard or substrate in enzymatic assays to study phospholipase activities and lipid signaling cascades.
• Lipidomics & Metabolomics: Serves as a critical reference compound for the identification and quantification of complex lipid species in mass spectrometry-based analyses.
• Pharmaceutical Development: Employed as a key raw material in the formulation of sophisticated lipid-based drug delivery vehicles, including targeted liposomes and solid lipid nanoparticles (SLNs).
• Cell Biology Studies: Utilized to investigate the role of specific phosphatidic acid species in membrane fusion, fission, and intracellular trafficking.
• Signal Transduction Research: Acts as a bioactive lipid to study its function as a second messenger in pathways involving cell growth, proliferation, and stress responses.
• Synthetic Lipid Chemistry: Provides a defined building block for the chemical or enzymatic synthesis of more complex, asymmetric phospholipids.

Basic Information

Product Name	1-Stearoyl-2-Arachidonoylphosphatidic Acid
CAS No.	119904-30-2
Molecular Formula	C41H73O8P
Molecular Weight	724.99 g/mol
Synonyms	PA(18:0/20:4); Phosphatidic Acid(18:0/20:4); 1-Octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate; (5Z,8Z,11Z,14Z)-Eicosatetraenoic Acid 1-[(1-O-Octadecanoyl-2-O-[(5Z,8Z,11Z,14Z)-1-oxo-5,8,11,14-eicosatetraen-1-yl]-sn-glycer-3-yl] Ester; 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphate; SAPA; 1-Stearoyl-2-Arachidonoyl PA
EINECS	Contact for details

Quality Control

Our 1-Stearoyl-2-Arachidonoylphosphatidic Acid is produced under stringent conditions to ensure batch-to-batch consistency and high chemical purity, suitable for sensitive research applications. Each lot is accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request, supporting compliance with rigorous internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Solubility	Soluble in chloroform, ethanol; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.