Description

3'-Azido-3'-Deoxyribavirin-5'-Triphosphate is a chemically modified nucleoside triphosphate analog, a critical building block for research in virology and nucleic acid chemistry. Its unique azido modification at the 3'-position makes it a valuable tool for studying viral polymerase mechanisms and for the development of chain-terminating antiviral agents. This high-purity biochemical is essential for researchers and developers in pharmaceutical R&D, diagnostic assay development, and advanced life science applications. CAS No. 119764-56-6.

Application

• Antiviral Research: Used as a substrate analog to study the inhibition and mechanisms of viral RNA-dependent RNA polymerases (RdRps).
• Probe Development: Serves as a key component in the synthesis of labeled probes for diagnostic and research applications.
• Nucleic Acid Chemistry: Acts as a specialized monomer for the enzymatic synthesis of modified oligonucleotides with specific termination properties.
• Biochemical Assays: Employed in high-throughput screening (HTS) platforms to identify novel antiviral compounds.
• Mechanistic Studies: Utilized to investigate nucleotide incorporation fidelity and chain termination events in polymerase reactions.
• Preclinical Drug Development: A vital intermediate in the research and development pathway for next-generation antiviral therapeutics.

Basic Information

Item	Detail
Product Name	3'-Azido-3'-Deoxyribavirin-5'-Triphosphate
CAS No.	119764-56-6
Molecular Formula	C9H14N6O13P3
Molecular Weight	546.15 g/mol
Synonyms	3'-Azido-3'-deoxyribavirin 5'-triphosphate; 3'-N3-ribavirin-TP; 3'-Azido-ribavirin triphosphate; Azidoribavirin triphosphate; Ribavirin 3'-azido-3'-deoxy-5'-triphosphate; 1-((2R,3R,4S,5R)-3-Azido-5-((hydroxy((hydroxy(phosphonooxy)phosphoryl)oxy)phosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide
EINECS	Contact for details

Quality Control

Every batch of 3'-Azido-3'-Deoxyribavirin-5'-Triphosphate is manufactured under stringent quality systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our quality commitment aligns with GMP principles for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for assay, purity by HPLC, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.