Description

Mofegiline CAS NO 119386-96-8 is a selective and irreversible inhibitor of monoamine oxidase B (MAO-B), a key enzyme in the central nervous system. This compound is of significant interest in pharmaceutical research and development for its potential neuropharmacological applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of treatments for neurological disorders such as Parkinson's disease.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel MAO-B inhibitors.
• Neuropharmacology Studies: Used in in vitro and in vivo studies to investigate the role of MAO-B in neurodegenerative processes and to evaluate therapeutic efficacy.
• Biochemical Assay Development: Employed as a specific enzyme inhibitor to validate assay systems targeting monoamine oxidase activity.
• Preclinical Formulation: Incorporated into formulation studies for potential drug candidates targeting central nervous system disorders.

Basic Information

Product Name	Mofegiline
CAS No.	119386-96-8
Molecular Formula	C13H19F2NO
Molecular Weight	243.29 g/mol
Synonyms	(E)-2-(Fluoromethyl)-3-fluoroallylamine; (E)-2-(Fluoromethyl)-3-fluoro-2-propen-1-amine; MDL-72974; pARGyline analog; MAO-B Inhibitor MDL 72974; (E)-2-(Fluoromethyl)-3-fluoroprop-2-en-1-amine
EINECS	Contact for details

Quality Control

Our Mofegiline is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity determination by HPLC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider keeping the material under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.