Description

3-Amino-2,4,5-Trifluorobenzoic Acid is a high-value fluorinated aromatic building block characterized by its unique combination of an amino group and a carboxylic acid on a trifluorinated benzene ring. This structure makes it a critical intermediate for the synthesis of complex molecules, particularly in advanced pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for constructing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for their unique electronic properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Amino-2,4,5-Trifluorobenzoic Acid
CAS No.	119385-80-7
Molecular Formula	C7H4F3NO2
Molecular Weight	191.11 g/mol
Synonyms	2,4,5-Trifluoro-3-aminobenzoic Acid; 3-Amino-2,4,5-trifluorobenzoic Acid; Benzoic acid, 3-amino-2,4,5-trifluoro-; 2,4,5-Trifluoro-m-aminobenzoic Acid; 3-Amino-2,4,5-trifluorobenzoic acid (ACI); 3-Amino-perfluoro-benzoic Acid; A2,4,5TF3ABA
EINECS	Contact for details

Quality Control

Every batch of 3-Amino-2,4,5-Trifluorobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as identity, purity, and impurity profile. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.