Description

2,4,5-Trifluoro-3-(Trifluoromethyl)Benzoic Acid is a high-value, multi-fluorinated aromatic building block essential for advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and multiple fluorine atoms on the benzoic acid core, makes it a critical intermediate for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, central nervous system (CNS), and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine motifs enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with improved chemical resistance, thermal stability, and surface properties.
• Organic Electronic Materials: Utilized in the development of electron-transport materials and semiconductors for OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile building block for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the exploration of new chemical spaces.

Basic Information

Item	Details
Product Name	2,4,5-Trifluoro-3-(Trifluoromethyl)Benzoic Acid
CAS No.	118829-14-4
Molecular Formula	C8H2F6O2
Molecular Weight	244.09 g/mol
Synonyms	3-(Trifluoromethyl)-2,4,5-trifluorobenzoic Acid; 2,4,5-Trifluoro-α,α,α-trifluoro-m-toluic Acid; 2,4,5-Trifluoro-3-trifluoromethylbenzoic Acid; Benzoic acid, 2,4,5-trifluoro-3-(trifluoromethyl)-; TFTBA; 118829-14-4
EINECS	Contact for details

Quality Control

Every batch of 2,4,5-Trifluoro-3-(Trifluoromethyl)Benzoic Acid is produced under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.