Description

3-Bromo-2,5,6-Trifluorobenzoic Acid is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it a versatile precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Serves as a critical building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Used in the research and production of advanced electronic materials, where its fluorine atoms contribute to desired dielectric and luminescent properties.
• Cross-Coupling Reactions: The bromine substituent acts as an excellent handle for palladium-catalyzed reactions (e.g., Suzuki, Stille), enabling rapid diversification of the benzoic acid core.
• Fluorine Chemistry Research: An important reagent for studying structure-activity relationships (SAR) and introducing fluorine atoms into complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and scaled-up processes.

Basic Information

Product Name	3-Bromo-2,5,6-Trifluorobenzoic Acid
CAS No.	118829-12-2
Molecular Formula	C7H2BrF3O2
Molecular Weight	260.99 g/mol
Synonyms	2,5,6-Trifluoro-3-bromobenzoic Acid; Benzoic acid, 3-bromo-2,5,6-trifluoro-; 3-Bromo-2,5,6-trifluorobenzoic acid; 118829-12-2; 2,5,6-Trifluoro-3-bromobenzoic acid; 3-Br-2,5,6-F3-BA
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2,5,6-Trifluorobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.