Description

(+)-1-(9-Fluorenyl)Ethyl Chloroformate is a chiral derivatizing agent of high purity, primarily used for the enantiomeric resolution and analysis of chiral compounds. Its value lies in its ability to form stable, UV-absorbing diastereomers with amines and amino acids, facilitating their separation and quantification via HPLC. This product is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and fine chemical sectors who require precise chiral analysis for drug development and quality assurance.

Application

• Chiral Derivatization for HPLC Analysis: Used to prepare diastereomeric derivatives of chiral amines, amino acids, and amino alcohols for enantiomeric purity determination.
• Pharmaceutical Research & Development: Critical for the stereochemical analysis of active pharmaceutical ingredients (APIs) and intermediates during drug discovery and process development.
• Quality Control in Manufacturing: Ensures enantiomeric purity and batch-to-batch consistency of chiral drugs and fine chemicals.
• Biochemical Research: Employed in the study of chiral metabolites, neurotransmitters, and other biologically active amines.
• Method Development & Validation: Serves as a standard reagent for developing and validating robust chiral analytical methods.
• Impurity Profiling: Helps identify and quantify trace enantiomeric impurities in bulk substances.

Basic Information

Product Name	(+)-1-(9-Fluorenyl)Ethyl Chloroformate
CAS No.	118609-65-7
Molecular Formula	C₁₇H₁₅ClO₂
Molecular Weight	286.75 g/mol
Synonyms	(+)-FLEC; (R)-(+)-1-(9-Fluorenyl)ethyl chloroformate; (R)-(+)-1-(9-Fluorenyl)ethyl chlorocarbonate; (+)-1-(9-Fluorenyl)ethyl chlorocarbonate; (R)-FLEC; (R)-(+)-FLEC; 1-(9H-Fluoren-9-yl)ethyl chloroformate, (1R)-; (1R)-1-(9H-Fluoren-9-yl)ethyl carbonochloridate
EINECS	Contact for details

Quality Control

Our (+)-1-(9-Fluorenyl)Ethyl Chloroformate is manufactured under strict quality systems to ensure high chemical and enantiomeric purity suitable for analytical applications. Each batch is tested to confirm identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.