Description

n-Pyrrolylpenicillin is a semi-synthetic penicillin derivative, representing a key intermediate in the development of novel β-lactam antibiotics. Its value lies in the structural modification of the penicillin core, which is critical for overcoming bacterial resistance mechanisms and expanding antimicrobial spectra. This compound is essential for pharmaceutical R&D teams and manufacturers focused on synthesizing next-generation antibacterial agents and studying structure-activity relationships.

Application

• Pharmaceutical Intermediate: Primary use as a crucial building block in the synthesis of advanced penicillin and cephalosporin analogs.
• Antibacterial Research: Serves as a key substrate in microbiological and pharmacological studies to evaluate new mechanisms of action against resistant pathogens.
• Medicinal Chemistry: Used in lead optimization programs to modify the side chain of β-lactam antibiotics, aiming to improve pharmacokinetic properties.
• API Development: Employed in the process development and scale-up of active pharmaceutical ingredients (APIs) within the antibacterial class.
• Academic & Institutional Research: Utilized in university and institutional labs for chemical biology studies related to bacterial cell wall synthesis inhibition.

Basic Information

Product Name	n-Pyrrolylpenicillin
CAS No.	117516-80-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2S,5R,6R)-6-[[(2R)-2-Amino-2-(1H-pyrrol-2-yl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; 6-(D-2-Amino-2-pyrrolylacetamido)penicillanic acid; Penicillin, 6-(2-amino-2-pyrrolylacetamido)-, (2S-(2alpha,5alpha,6beta))-; Pyrrolylpenicillin; n-Pyrrolyl penicillin
EINECS	Contact for details

Quality Control

Our n-Pyrrolylpenicillin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.