Description

Deoxy(Thymidylic-Adenylic-Cytidylic-Guanosine) is a defined-sequence oligonucleotide, a critical building block in molecular biology and genetic research. This compound is essential for applications requiring precise nucleic acid sequences, such as primer and probe synthesis. It is primarily utilized by research institutions, diagnostic kit manufacturers, and biotechnology companies engaged in PCR, sequencing, and gene synthesis. The product, identified by CAS No. 117489-85-7, is supplied to meet the stringent purity demands of advanced life science applications.

Application

• Primer Synthesis for PCR (Polymerase Chain Reaction): Used as a core component for manufacturing specific primers in diagnostic and research PCR assays.
• Fluorescent Probe Development: Serves as a backbone for constructing hybridization probes used in real-time PCR and FISH (Fluorescence In Situ Hybridization).
• Gene Synthesis and Cloning: Acts as a fundamental unit in the de novo chemical synthesis of longer DNA fragments for gene construction and molecular cloning.
• Antisense Oligonucleotide Research: Provides a defined sequence for studying gene function and regulation in therapeutic discovery pipelines.
• Diagnostic Kit Manufacturing: Incorporated into standardized kits for infectious disease testing, genetic screening, and companion diagnostics.
• Next-Generation Sequencing (NGS): Used in the preparation of adapters, barcodes, and other oligonucleotide tools essential for NGS library construction.
• Quality Control Standards: Employed as a reference standard or control material in QC laboratories to validate oligonucleotide synthesis and analysis processes.

Basic Information

Product Name	Deoxy(Thymidylic-Adenylic-Cytidylic-Guanosine)
CAS No.	117489-85-7
Molecular Formula	C39H49N15O23P4
Molecular Weight	1223.81 g/mol
Synonyms	d(TACG); TACG Tetramer; Deoxythymidylyl-(3'→5')-deoxyadenylyl-(3'→5')-deoxycytidylyl-(3'→5')-deoxyguanosine; Oligonucleotide d(TACG); DNA Tetramer T-A-C-G; 5'-d(TpApCpG)-3'; Thymidylic-adenylic-cytidylic-guanosine tetranucleotide
EINECS	Contact for details

Quality Control

Our oligonucleotides are manufactured under controlled conditions and subjected to rigorous analytical testing to ensure sequence fidelity and high purity. Each batch is analyzed by HPLC and Mass Spectrometry (MS) to confirm identity and assess purity levels suitable for sensitive molecular biology applications. Certificates of Analysis (COA) detailing purity, concentration, and analytical results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Extinction Coefficient	Provided on COA
Molecular Weight	1223.81 g/mol (Theoretical)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.