Description

9-(4-Hydroxy-2-(Hydroxymethyl)Butyl)-Guanine Triphosphate is a chemically modified nucleotide analog of guanosine triphosphate (GTP). This compound is of significant value in biochemical and pharmaceutical research, particularly as a substrate or inhibitor for studying enzyme kinetics and nucleotide-dependent processes. It is primarily needed by research institutions, biotechnology companies, and pharmaceutical developers working in areas such as antiviral drug discovery, molecular biology, and enzymology.

Application

• Biochemical Research: Used as a specialized substrate or competitive inhibitor in enzymatic assays to study GTP-binding proteins (G-proteins), polymerases, and kinases.
• Antiviral Drug Development: Serves as a potential nucleotide analog for probing the mechanisms of viral replication and as a lead compound in the design of novel antiviral therapeutics.
• Molecular Biology: Employed in studies of nucleic acid metabolism, RNA synthesis, and signal transduction pathways that involve GTP as a cofactor.
• Enzymology Studies: Acts as a tool compound to investigate the specificity and catalytic mechanisms of nucleotide-processing enzymes.
• Diagnostic Reagent Manufacturing: Can be incorporated into the development of high-sensitivity diagnostic kits and assays for research use.

Basic Information

Product Name	9-(4-Hydroxy-2-(Hydroxymethyl)Butyl)-Guanine Triphosphate
CAS No.	117191-32-9
Molecular Formula	C11H18N5O13P3
Molecular Weight	545.21 g/mol
Synonyms	9-[(4-Hydroxy-2-(hydroxymethyl)butyl)]guanine triphosphate; (2'R)-9-[2-(Hydroxymethyl)-4-hydroxybutyl]guanine triphosphate; H2G-TP; Modified GTP analog; Acyclovir guanosine triphosphate analog; BMS-200475-TP; Entecavir triphosphate analog
EINECS	Contact for details

Quality Control

Our 9-(4-Hydroxy-2-(Hydroxymethyl)Butyl)-Guanine Triphosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water or suitable aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.