Description

3-Nitro-4-(Trifluoromethyl)Benzoic Acid is a high-value, multi-functional aromatic building block characterized by its electron-withdrawing nitro and trifluoromethyl substituents. This compound is essential for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where its unique structure imparts critical properties like metabolic stability and lipophilicity. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for use in drug discovery and the development of performance materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for creating molecules with enhanced bioavailability and target specificity.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for electronic chemicals used in display technologies and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter thermal, chemical, or surface properties for high-performance applications.
• Dye & Pigment Intermediate: Utilized in the synthesis of complex colorants and pigments for specialized industrial uses.
• Organic Synthesis & Research Chemical: A versatile reagent in academic and industrial R&D labs for constructing complex aromatic systems and exploring new chemical reactions.

Basic Information

Product Name	3-Nitro-4-(Trifluoromethyl)Benzoic Acid
CAS No.	116965-16-3
Molecular Formula	C8H4F3NO4
Molecular Weight	235.12 g/mol
Synonyms	4-(Trifluoromethyl)-3-nitrobenzoic acid; 3-Nitro-4-trifluoromethylbenzoic acid; Benzoic acid, 3-nitro-4-(trifluoromethyl)-; 3-Nitro-α,α,α-trifluoro-p-toluic acid; 2-Nitro-4-carboxybenzotrifluoride; 4-Carboxy-2-nitrobenzotrifluoride; NSC 405124; 116965-16-3
EINECS	Contact for details

Quality Control

Our 3-Nitro-4-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.