Description

3-Hydroxy-2,4,5-Trifluorobenzoic Acid is a fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique trifluorinated pattern adjacent to a phenolic hydroxyl group makes it a valuable intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Building block for developing next-generation herbicides, fungicides, and pesticides, where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Used in the research and production of fluorinated organic electronic materials for displays and lighting applications.
• Advanced Polymer Chemistry: Monomer or modifier for engineering high-performance, specialty polymers with enhanced chemical and thermal resistance.
• Chemical Research & Development: Versatile scaffold in medicinal and process chemistry for structure-activity relationship (SAR) studies and route scouting.
• Complex Ligand Synthesis: Starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Hydroxy-2,4,5-Trifluorobenzoic Acid
CAS No.	116751-24-7
Molecular Formula	C7H3F3O3
Molecular Weight	192.09 g/mol
Synonyms	2,4,5-Trifluoro-3-hydroxybenzoic Acid; 3-Hydroxy-2,4,5-trifluorobenzoic Acid; Benzoic acid, 2,4,5-trifluoro-3-hydroxy-; 2,4,5-Trifluoro-3-hydroxybenzoic acid; 3-Hydroxy-2,4,5-trifluorobenzoic acid (CAS 116751-24-7)
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for 3-Hydroxy-2,4,5-Trifluorobenzoic Acid, ensuring batch-to-batch consistency and high purity suitable for sensitive synthetic applications. Our quality system includes identity confirmation, purity assay, and impurity profiling via modern analytical techniques. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.