Description

Katanosin A CAS NO 116103-86-7 is a complex cyclic lipopeptide antibiotic belonging to the katanosin family. This compound is valued for its potent activity against Gram-positive bacteria, including multidrug-resistant strains such as methicillin-resistant *Staphylococcus aureus* (MRSA) and vancomycin-resistant enterococci (VRE). It is primarily utilized in advanced pharmaceutical research and development for investigating novel antimicrobial mechanisms and as a critical reference standard in analytical laboratories.

Application

• Antimicrobial Research: Serves as a key investigational compound for studying novel modes of action against resistant Gram-positive pathogens.
• Pharmaceutical R&D: Used as a lead structure or a biological tool in the discovery and development of new antibiotic therapies.
• Analytical Reference Standard: Essential for the qualitative and quantitative analysis (HPLC, LC-MS) of katanosin compounds in quality control and method development.
• Mechanistic Studies: Employed in biochemical and microbiological assays to understand bacterial cell wall biosynthesis inhibition.
• Academic Research: Used in university and institutional labs for fundamental research on antibiotic resistance and peptide chemistry.

Basic Information

Product Name	Katanosin A
CAS No.	116103-86-7
Molecular Formula	C72H101N15O22
Molecular Weight	1560.7 g/mol
Synonyms	Katanosin A; Lysobactin; Antibiotic A-21978C1; Leu-Katanosin A; Cilamycin; (3S)-3-Amino-4-[[(2S,3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-3-methylpentanoyl]amino]-5-guanidino-4-oxopentanoic acid
EINECS	Contact for details

Quality Control

Our Katanosin A is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and NMR for structural verification, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. Due to its hygroscopic (moisture-sensitive) nature, the product should be handled under anhydrous conditions and allowed to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Biological Activity	Assay available upon request

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.