Description

3-Fluoro-4-(Trifluoromethyl)Benzoic Acid is a high-value fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group, imparts significant electronic and steric properties that are critical for modifying the activity and stability of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Incorporated into specialty polymers to improve chemical resistance, thermal stability, and surface properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for studying fluorination effects and developing novel catalytic processes.
• Advanced Material Science: Used in the synthesis of ligands for metal-organic frameworks (MOFs) and other functional materials.

Basic Information

Item	Detail
Product Name	3-Fluoro-4-(Trifluoromethyl)Benzoic Acid
CAS No.	115754-21-7
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	3-Fluoro-4-(trifluoromethyl)benzoic acid; 4-(Trifluoromethyl)-3-fluorobenzoic acid; Benzoic acid, 3-fluoro-4-(trifluoromethyl)-; 3-Fluoro-α,α,α-trifluoro-p-toluic acid; 3-Fluoro-4-trifluoromethylbenzoic acid; 115754-21-7; 3-Fluoro-4-trifluoromethyl-benzoic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Trifluoromethyl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the stringent requirements of our global clientele. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to support regulatory filings (e.g., FDA DMF, CEP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.