Description

2-(3,4-Dichlorophenyl)-n-Methyl-n-[(1S)-1-Phenyl-2-(1-Pyrrolidinyl)Ethyl]Acetamide Hydrochloride is a high-purity chiral organic compound of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture, featuring a stereogenic center and multiple functional groups, makes it a valuable pharmacological intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Chemical Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related pharmaceutical substances.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for complex, stereospecific molecules.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis, asymmetric catalysis, and pharmacology.

Basic Information

Item	Detail
Product Name	2-(3,4-Dichlorophenyl)-n-Methyl-n-[(1S)-1-Phenyl-2-(1-Pyrrolidinyl)Ethyl]Acetamide Hydrochloride
CAS No.	115199-84-3
Molecular Formula	C21H23Cl2N2O • HCl
Molecular Weight	419.79 g/mol (Free base: 383.33 g/mol)
Synonyms	N-Methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]-2-(3,4-dichlorophenyl)acetamide hydrochloride; (S)-N-Methyl-N-(1-phenyl-2-(pyrrolidin-1-yl)ethyl)-2-(3,4-dichlorophenyl)acetamide HCl; Levomilnacipran related compound; F2695; 1-Phenyl-2-(1-pyrrolidinyl)-1-(2-(3,4-dichlorophenyl)acetamido)ethane hydrochloride (S-isomer); Milnacipran impurity; Chiral acetamide derivative.
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dichlorophenyl)-n-Methyl-n-[(1S)-1-Phenyl-2-(1-Pyrrolidinyl)Ethyl]Acetamide Hydrochloride is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. We adhere to ICH guidelines for stability and impurity profiling. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and related substances, available upon request. Our quality commitment supports compliance in cGMP environments for pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (S-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%; Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.