Description

D-Luciferin Potassium Salt is a high-purity, water-soluble derivative of D-luciferin, a critical substrate for the firefly luciferase enzyme. This compound is essential for generating bioluminescent signals in a wide range of life science research and drug discovery applications. It is primarily used by researchers and scientists in the pharmaceutical, biotechnology, and academic sectors for sensitive detection and quantification in assays such as ATP monitoring, cell viability, and in vivo imaging.

Application

• Bioluminescence Imaging (BLI): A key substrate for non-invasive, real-time monitoring of tumor growth, gene expression, and cell trafficking in live animal models.
• ATP-Dependent Assays: Used in cell viability, cytotoxicity, and proliferation assays to measure cellular ATP levels as an indicator of metabolic activity.
• Reporter Gene Assays: Enables high-throughput screening (HTS) in drug discovery by quantifying luciferase reporter gene activity for studying promoter function, signal transduction, and gene regulation.
• Microbial Detection: Applied in hygiene monitoring and environmental testing to detect microbial contamination via ATP-bioluminescence.
• In Vitro Diagnostics: Utilized in diagnostic kits for sensitive detection of specific enzymes or biomarkers.
• Basic Research: Fundamental tool for studying bioluminescence mechanisms, enzyme kinetics, and developing novel biosensors.

Basic Information

Product Name	D-Luciferin Potassium Salt
CAS No.	115144-35-9
Molecular Formula	C11H7K2N2O3S2
Molecular Weight	318.42 g/mol
Synonyms	D-(-)-Luciferin Potassium Salt; Firefly Luciferin Potassium Salt; Beetle Luciferin Potassium Salt; (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic Acid Potassium Salt; Potassium D-Luciferin; D-Luciferin, K+ salt; Luciferin K Salt; LH2-K
EINECS	Contact for details

Quality Control

Our D-Luciferin Potassium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	95.0% - 105.0%
Water Content (KF)	≤ 2.0%
Bioluminescence Activity	Conforms to reference standard
Solubility (in water)	Clear, yellow solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.