Description

2-Fluoro-4-(Trifluoromethyl)Benzoic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its unique trifluoromethyl and fluorine substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS, oncology, and anti-inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays (LCDs) due to its ability to influence dielectric anisotropy and viscosity.
• Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with improved chemical resistance, thermal stability, and surface properties.
• Organic Electronics: Used in the development of materials for organic light-emitting diodes (OLEDs) and semiconductors, where fluorination improves electron affinity and device efficiency.
• Chemical Research & Development: A versatile building block for exploring new chemical spaces in academic and industrial R&D laboratories, enabling the synthesis of complex, fluorinated molecular architectures.

Basic Information

Product Name	2-Fluoro-4-(Trifluoromethyl)Benzoic Acid
CAS No.	115029-24-8
Molecular Formula	C8H4F4O2
Molecular Weight	208.11 g/mol
Synonyms	2-Fluoro-α,α,α-trifluoro-p-toluic acid; 4-(Trifluoromethyl)-2-fluorobenzoic acid; Benzoic acid, 2-fluoro-4-(trifluoromethyl)-; 2-Fluoro-4-trifluoromethylbenzoic acid; 2-Fluoro-α,α,α-trifluoro-4-methylbenzoic acid; 2-Fluoro-4-(trifluoromethyl)benzenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.