Description

2,4,5-Trifluoro-3-Methylbenzoic Acid is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters because its unique trifluoromethyl and benzoic acid structure provides critical properties for developing active pharmaceutical ingredients and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries seeking to introduce fluorine atoms for enhanced metabolic stability, lipophilicity, and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine atoms improve biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in high-performance displays.
• Polymer Chemistry: Incorporated as a monomer or modifier to create fluorinated polymers with enhanced chemical resistance, thermal stability, and low surface energy.
• Organic Electronics: Utilized in the synthesis of electron-transport materials and semiconductors for OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile building block for Suzuki-Miyaura and other cross-coupling reactions to create complex, multi-substituted aromatic systems.

Basic Information

Product Name	2,4,5-Trifluoro-3-Methylbenzoic Acid
CAS No.	112822-85-2
Molecular Formula	C8H5F3O2
Molecular Weight	190.12 g/mol
Synonyms	3-Methyl-2,4,5-trifluorobenzoic Acid; 2,4,5-Trifluoro-m-toluic Acid; Benzoic acid, 2,4,5-trifluoro-3-methyl-; 2,4,5-Trifluoro-3-methylbenzenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluoro-3-Methylbenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.