Description

3-Methoxy-2,4,5-Trifluorobenzamide is a high-purity fluorinated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials that require a precisely substituted benzamide core.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the trifluoromethyl and methoxy groups confer desirable biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), enhancing performance characteristics.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways and creating libraries of fluorinated compounds for screening.
• Advanced Polymer Modification: Acts as a monomer or modifier to introduce fluorine atoms into polymer backbones, improving chemical resistance and material properties.

Basic Information

Product Name	3-Methoxy-2,4,5-Trifluorobenzamide
CAS No.	112811-64-0
Molecular Formula	C8H6F3NO2
Molecular Weight	211.13 g/mol
Synonyms	2,4,5-Trifluoro-3-methoxybenzamide; Benzamide, 2,4,5-trifluoro-3-methoxy-; 3-Methoxy-2,4,5-trifluorobenzoic acid amide; 2,4,5-Trifluoro-m-anisamide; 3-Methoxy-2,4,5-trifluorobenzamide (primary IUPAC); 2,4,5-Trifluoro-3-methoxybenzenecarboxamide
EINECS	Contact for details

Quality Control

Our 3-Methoxy-2,4,5-Trifluorobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.