Description

2-Fluoro-6-Iodobenzoic Acid is a high-purity, multi-functional halogenated benzoic acid derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, provides exceptional versatility for creating complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries, where it is used to synthesize novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic scaffolds for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, where the halogen atoms can be leveraged for binding specificity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where halogenated benzoic acids modify electronic properties.
• Chemical Biology Probes: Utilized to create tagged molecules or probes for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl structures.

Basic Information

Product Name	2-Fluoro-6-Iodobenzoic Acid
CAS No.	111771-08-5
Molecular Formula	C7H4FIO2
Molecular Weight	265.01 g/mol
Synonyms	6-Iodo-2-fluorobenzoic Acid; Benzoic acid, 2-fluoro-6-iodo-; 2-Fluoro-6-iodobenzenecarboxylic acid; 2-Fluoro-6-iodo-benzoic acid; 111771-08-5; 2-Fluoro-6-iodobenzoicacid; 2-Fluoro-6-jodbenzoesäure (German); Acide 2-fluoro-6-iodobenzoïque (French)
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-Iodobenzoic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support compliance in cGMP and ISO 9001 environments where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.