Description

4-Methoxy-2,3,5,6-Tetrafluorobenzoyl Chloride is a highly reactive and versatile fluorinated aromatic acid chloride derivative. This compound is a critical building block in advanced organic synthesis, valued for its ability to introduce the electron-deficient tetrafluoromethoxybenzoyl moiety into target molecules. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates with enhanced properties.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated aromatic groups to modulate lipophilicity, metabolic stability, and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the fluorinated aromatic structure contributes to efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated liquid crystals for display technologies.
• Polymer Chemistry: Acts as a monomer or modifying agent for creating specialty polymers with specific thermal, chemical, or surface properties.
• Organic Synthesis Reagent: Employed in amide coupling reactions, esterifications, and Friedel-Crafts acylations in research and fine chemical production.
• Material Science: Used in surface functionalization and the creation of advanced organic frameworks and coatings.

Basic Information

Product Name	4-Methoxy-2,3,5,6-Tetrafluorobenzoyl Chloride
CAS No.	107535-74-0
Molecular Formula	C8H3ClF4O2
Molecular Weight	242.56 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-methoxybenzoyl chloride; 4-Methoxy-2,3,5,6-tetrafluorobenzoic acid chloride; Perfluoro-4-methoxybenzoyl chloride; Tetrafluoro-4-methoxybenzoyl chloride; 4-Methoxytetrafluorobenzoyl chloride; α,α,α,α-Tetrafluoro-4-methoxybenzoyl chloride; 2,3,5,6-Tetrafluoro-p-anisoyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2,3,5,6-Tetrafluorobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.