Description

Conus Magus Toxin CAS NO 107407-86-3 is a highly specific and potent peptide neurotoxin derived from the venom of the marine cone snail, *Conus magus*. This compound is of critical importance in neuroscience research as a selective N-type voltage-gated calcium channel blocker. It is primarily needed by pharmaceutical researchers, neuroscientists, and biochemical suppliers for use in neurological studies, ion channel research, and the development of novel therapeutic agents for pain management.

Application

• Neuroscience Research: A key tool for studying N-type calcium channel function and neuronal signaling pathways.
• Ion Channel Pharmacology: Used to characterize and validate calcium channel subtypes in drug discovery assays.
• Pain Research: Investigated as a template for developing non-opioid analgesic drugs due to its potent channel-blocking activity.
• Biochemical Standard: Serves as a high-purity reference standard for analytical and quality control purposes.
• Cellular Physiology Studies: Applied in experiments to understand calcium-dependent processes like neurotransmitter release.
• Toxicology Studies: Used in research on marine toxins and their mechanisms of action.

Basic Information

Item	Detail
Product Name	Conus Magus Toxin
CAS No.	107407-86-3
Molecular Formula	C158H246N46O45S5
Molecular Weight	~2639.1 g/mol
Synonyms	ω-Conotoxin MVIIA; SNX-111; Ziconotide (Pharmaceutical Grade); CTx-MVIIA; ω-Conotoxin MVIIA; CmTx; Conus magus Peptide Toxin; N-type Calcium Channel Blocker
EINECS	Contact for details

Quality Control

Our Conus Magus Toxin is produced and tested under stringent conditions to ensure the highest standards of purity and biological activity, suitable for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and identity. We adhere to relevant quality guidelines for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider aliquoting to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Potency)	≥ 98% (by functional assay)
Water Content (KF)	≤ 5.0%
Endotoxin Level	< 1.0 EU/µg
Solubility	Soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.