Description

Tamsulosin Hydrochloride CAS NO 106463-17-6 is a highly selective α-1A and α-1D adrenergic receptor antagonist. This compound is of critical importance as the active pharmaceutical ingredient (API) in medications used to treat benign prostatic hyperplasia (BPH). It is primarily required by pharmaceutical manufacturers and research institutions for the formulation of finished dosage forms and clinical studies. Consistent quality and reliable supply are paramount for ensuring the efficacy and safety of the final therapeutic products.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for the treatment of lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).
• Generic Drug Manufacturing: Sourcing for the production of generic tamsulosin hydrochloride tablets and capsules following patent expirations.
• Clinical Research: Utilization in bioavailability, bioequivalence, and new formulation development studies.
• Controlled-Release Formulations: Key component in the development of modified-release drug delivery systems to provide sustained therapeutic effect.
• Reference Standard: Serves as a high-purity chemical reference standard for quality control and analytical testing in pharmaceutical laboratories.
• Preclinical Studies: Used in pharmacological research to study adrenergic receptor mechanisms and urological pharmacology.

Basic Information

Product Name	Tamsulosin Hydrochloride
CAS No.	106463-17-6
Molecular Formula	C20H28N2O5S • HCl
Molecular Weight	444.98 g/mol
Synonyms	(-)-(R)-5-[2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide Hydrochloride; Tamsulosin HCl; AMR-69; YM-617; Flomax (Brand Name); Harnal (Brand Name); Omnic (Brand Name); (R)-Tamsulosin Hydrochloride
EINECS	Contact for details

Quality Control

Our Tamsulosin Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines and current Good Manufacturing Practices (GMP). A detailed Certificate of Analysis (COA) providing batch-specific results for all critical parameters is available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.5% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any individual impurity ≤ 0.5%
Optical Rotation	-10.0° to -12.0° (c=1 in methanol)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.