Description

R-Bacampicillin is a semi-synthetic, prodrug form of ampicillin, designed for enhanced oral bioavailability and stability. This compound is of significant value in pharmaceutical research and development, particularly for studying antibiotic delivery and efficacy. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of advanced β-lactam antibiotics and prodrug formulations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active ampicillin for antibiotic formulations.
• Antibacterial Research: Used in microbiological and pharmacological studies to investigate the mechanisms of prodrug activation and bacterial resistance.
• Prodrug Development: Serves as a model compound for designing and evaluating novel ester-based prodrugs to improve drug absorption and patient compliance.
• Analytical Reference Standard: Employed as a high-purity standard in quality control laboratories for HPLC, LC-MS, or NMR analysis of antibiotic products.
• Academic & Institutional Research: Utilized in university and government labs for biochemical and medicinal chemistry research projects.

Basic Information

Product Name	R-Bacampicillin
CAS No.	106449-06-3
Molecular Formula	C21H27N3O7S
Molecular Weight	465.52 g/mol
Synonyms	Bacampicillin; (1'S)-1'-[(2,2-Dimethylpropanoyl)oxy]ethyl (2R,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate; (R)-Bacampicillin; Ampicillin Prodrug; Ambaxin; Penglobe; Spectrobid; Bacacil; Bacampicillin Hydrochloride (related salt form)
EINECS	Contact for details

Quality Control

Our R-Bacampicillin is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Each lot is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling via advanced techniques like HPLC and NMR. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.