Description

n-(3-Dimethylaminopropyl)Benzylpenicillinamide is a chemically modified penicillin derivative, specifically a penicillinamide, designed for advanced pharmaceutical research and synthesis. This compound matters as a key intermediate or building block in the development of novel β-lactam antibiotics and other bioactive molecules, offering researchers a versatile scaffold for structural modification. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in antimicrobial drug discovery and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel penicillin and cephalosporin analogs for antimicrobial research.
• Medicinal Chemistry Research: Used as a building block for structure-activity relationship (SAR) studies to develop new β-lactamase inhibitors.
• Bioconjugation & Probe Development: The reactive amide and amine functional groups facilitate its use in creating labeled compounds for biochemical assays.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing of specialized, high-value chemical entities.
• Academic & Institutional Research: A valuable reagent for universities and research institutes studying antibiotic resistance mechanisms.

Basic Information

Product Name	n-(3-Dimethylaminopropyl)Benzylpenicillinamide
CAS No.	105603-45-0
Molecular Formula	C20H29N3O4S
Molecular Weight	407.53 g/mol
Synonyms	Benzylpenicillin N-(3-Dimethylaminopropyl)amide; Penicillin G 3-Dimethylaminopropylamide; 6-Phenylacetamidopenicillanic Acid N-(3-Dimethylaminopropyl)amide; N-(3-Dimethylaminopropyl)-benzylpenicillinamide; 105603-45-0; (2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (3-dimethylaminopropyl)amide
EINECS	Contact for details

Quality Control

Our n-(3-Dimethylaminopropyl)Benzylpenicillinamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.