Description

Methyl 2-Amino-4-Chloro-5-Fluorobenzoate is a high-purity fluorinated benzoate ester derivative, serving as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. Its value lies in its multifunctional molecular structure, which allows for precise chemical modifications essential for developing active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds and optimizing synthetic routes.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules, particularly those requiring fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the chloro-fluoro substitution pattern is beneficial.
• Organic Synthesis Reagent: Serves as a versatile precursor for further functionalization, including amide formation, coupling reactions, and heterocycle synthesis.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Methyl 2-Amino-4-Chloro-5-Fluorobenzoate
CAS No.	104901-79-3
Molecular Formula	C8H7ClFNO2
Molecular Weight	203.60 g/mol
Synonyms	2-Amino-4-chloro-5-fluorobenzoic acid methyl ester; Methyl 2-amino-4-chloro-5-fluorobenzoate; Benzoic acid, 2-amino-4-chloro-5-fluoro-, methyl ester; 4-Chloro-5-fluoro-2-aminobenzoic acid methyl ester; Methyl 4-chloro-5-fluoroanthranilate; 5-Fluoro-4-chloro-2-aminobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-4-Chloro-5-Fluorobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.