Description

2'-Fluorobiphenyl-3-Carboxylic Acid is a high-purity fluorinated biphenyl derivative serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine substituent and carboxylic acid group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in non-steroidal anti-inflammatory drugs (NSAIDs) and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorobiphenyl core contributes to biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies, leveraging its rigid biphenyl structure.
• Organic Light-Emitting Diodes (OLEDs): Acts as a building block for electron-transport or host materials in OLED devices due to its electronic properties.
• Cross-Coupling Reactions: The carboxylic acid functionality allows for easy conversion to esters, amides, or acid chlorides, facilitating Suzuki, Heck, and other palladium-catalyzed couplings.
• Material Science Research: Employed in the development of novel polymers and advanced organic frameworks with tailored thermal and chemical properties.

Basic Information

Product Name	2'-Fluorobiphenyl-3-Carboxylic Acid
CAS No.	103978-23-0
Molecular Formula	C13H9FO2
Molecular Weight	216.21 g/mol
Synonyms	[2-Fluorophenyl]-3-benzoic Acid; 3-Biphenylcarboxylic Acid, 2'-Fluoro-; 2'-Fluoro-3-biphenylcarboxylic Acid; 2-Fluoro-3-phenylbenzoic Acid; 2'-Fluoro[1,1'-biphenyl]-3-carboxylic Acid; NSC 405122; BRN 2938305; 3-Carboxy-2'-fluorobiphenyl
EINECS	Contact for details

Quality Control

Our 2'-Fluorobiphenyl-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with complete batch data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.