Description

n-(3,5-Dinitrobenzoyl)-L-Proline is a chiral derivatizing agent and analytical reagent of high purity. This compound is specifically engineered for the resolution and analysis of enantiomers, a critical process in pharmaceutical and fine chemical development. It is an essential tool for research laboratories and quality control units requiring precise chiral separation and identification.

Application

• Chiral derivatizing agent for High-Performance Liquid Chromatography (HPLC) analysis.
• Resolution of racemic mixtures of amino acids and other chiral amines.
• Preparation of diastereomeric derivatives for Nuclear Magnetic Resonance (NMR) spectroscopy studies.
• Quality control and purity assessment of enantiomerically pure pharmaceutical intermediates.
• Research and development of asymmetric synthesis methodologies.
• Analytical standard for method development and validation in chiral separations.

Basic Information

Product Name	n-(3,5-Dinitrobenzoyl)-L-Proline
CAS No.	103238-71-7
Molecular Formula	C₁₂H₁₁N₃O₇
Molecular Weight	309.23 g/mol
Synonyms	(S)-1-[(3,5-Dinitrobenzoyl)]pyrrolidine-2-carboxylic acid; L-Proline, N-(3,5-dinitrobenzoyl)-; DNBP; 3,5-Dinitrobenzoyl-L-proline; (S)-N-(3,5-Dinitrobenzoyl)proline; Chiral Derivatization Reagent DNBP-Pro; Marfey's reagent derivative
EINECS	Contact for details

Quality Control

Our n-(3,5-Dinitrobenzoyl)-L-Proline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for analytical and research applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible performance and reliable results in your chiral separation workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.