Description

Dansyl-Dl-Glutamic Acid is a fluorescently labeled derivative of the amino acid glutamic acid, featuring the dansyl chromophore. This compound is a critical reagent in biochemical research and analytical chemistry, primarily valued for its strong fluorescence properties which enable sensitive detection and quantification. It is essential for scientists and manufacturers in the fields of pharmaceutical development, proteomics, and analytical method validation, where precise labeling and tracing of amino acids and peptides are required.

Application

• Fluorescent Labeling Agent: Used as a derivatization reagent for the pre- or post-column labeling of amino acids, peptides, and proteins in High-Performance Liquid Chromatography (HPLC) for enhanced detection sensitivity.
• Biochemical Research: Serves as a key substrate or standard in enzyme activity assays, receptor-ligand binding studies, and metabolic pathway analysis involving glutamic acid.
• Proteomics & Peptide Synthesis: Employed in the synthesis and characterization of fluorescently tagged peptides to study protein structure, function, and interactions.
• Analytical Method Development: Acts as a reference standard for developing and validating chromatographic (HPLC, LC-MS) and spectroscopic methods for amino acid analysis.
• Neuroscience Research: Utilized in studies related to glutamate, a major neurotransmitter, to trace and visualize its uptake and metabolism.
• Quality Control Standards: Provides a high-purity chemical standard for the quality assurance testing of related pharmaceutical intermediates and biochemical kits.

Basic Information

Product Name	Dansyl-Dl-Glutamic Acid
CAS No.	102783-69-7
Molecular Formula	C₁₇H₂₂N₂O₆S
Molecular Weight	382.43 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonyl-DL-glutamic acid; Dansyl-DL-glutamate; N-Dansyl-DL-glutamic acid; DNS-DL-Glu; DL-Glutamic acid N-(5-dimethylaminonaphthalene-1-sulfonyl); 1-Dimethylaminonaphthalene-5-sulfonyl-DL-glutamic acid; N-(1-Dimethylaminonaphthalene-5-sulfonyl)-DL-glutamic acid
EINECS	Contact for details

Quality Control

Our Dansyl-Dl-Glutamic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions of 2-8°C.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.