Description

3,5-Dichloro-2,4-Difluoro-Benzoyl Fluoride is a high-purity, multi-halogenated aromatic building block of significant synthetic utility. This compound is a critical intermediate in the synthesis of advanced active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogen pattern enables precise molecular modifications. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic systems.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel fluorinated and chlorinated drug candidates, particularly in antimicrobial and anticancer research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the halogen atoms contribute to biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic cores used in electronic display technologies.
• Polymer Modification: Employed to introduce halogenated benzoyl groups into polymer chains, altering thermal and chemical resistance properties.
• Cross-Coupling Reactions: The benzoyl fluoride moiety and halogen substituents make it a valuable substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions.
• Organic Synthesis Reagent: Used in academic and industrial laboratories for the preparation of complex fluorinated and chlorinated aromatic compounds.

Basic Information

Product Name	3,5-Dichloro-2,4-Difluoro-Benzoyl Fluoride
CAS No.	101513-70-6
Molecular Formula	C7HCl2F3O
Molecular Weight	228.98 g/mol
Synonyms	3,5-Dichloro-2,4-difluorobenzoyl fluoride; 2,4-Difluoro-3,5-dichlorobenzoyl fluoride; Benzoyl fluoride, 3,5-dichloro-2,4-difluoro-; 3,5-Dichloro-2,4-difluorobenzoic acid fluoride
EINECS	Contact for details

Quality Control

Our 3,5-Dichloro-2,4-Difluoro-Benzoyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.