Description

1,2-Dielaidoyl-Sn-Glycero-3-Phosphoethanolamine is a synthetic, unsaturated phospholipid with a defined fatty acid composition, specifically featuring elaidic acid chains. This compound is a critical research-grade biochemical for studying membrane biophysics, lipid-protein interactions, and the effects of *trans* fatty acids on cellular processes. It is essential for scientists and manufacturers in lipidomics research, pharmaceutical development, and the formulation of advanced liposomal drug delivery systems where precise lipid composition is paramount.

Application

• Biophysical Research: A key component in model membrane systems (e.g., liposomes, bilayers) for studying phase behavior, permeability, and membrane fluidity.
• Lipidomics & Analytical Standards: Used as a high-purity reference standard for the identification and quantification of phospholipids in mass spectrometry and chromatography.
• Drug Delivery Development: Incorporated into liposomal and nanoparticle formulations to investigate the impact of *trans*-unsaturated lipids on stability, targeting, and release profiles.
• Cell Biology Studies: Employed to probe the biological effects of elaidic acid incorporation into cellular membranes and its role in signaling pathways.
• Pharmaceutical Excipient Research: Evaluated as a potential functional component in advanced parenteral formulations and diagnostic agents.

Basic Information

Product Name	1,2-Dielaidoyl-Sn-Glycero-3-Phosphoethanolamine
CAS No.	19805-18-6
Molecular Formula	C41H78NO8P
Molecular Weight	744.03 g/mol
Synonyms	1,2-Dielaidoylphosphatidylethanolamine; Dielaidoyl PE; trans-9-Octadecenoic acid 1,1'-[1,2-diacyl-sn-glycero-3-phosphoethyl] ester; PE(18:1(9E)/18:1(9E)); 1,2-Di-(9E-octadecenoyl)-sn-glycero-3-phosphoethanolamine; (9E,9'E)-1,2-Dioctadec-9-enoyl-sn-glycero-3-phosphoethanolamine; Phosphatidylethanolamine (dielaidoyl)
EINECS	Contact for details

Quality Control

Our high-purity biochemicals are produced and tested under strict quality management protocols. Each batch of 1,2-Dielaidoyl-Sn-Glycero-3-Phosphoethanolamine undergoes comprehensive analysis, including chromatographic purity assessment and structural confirmation, to ensure it meets exacting research standards. A detailed Certificate of Analysis (COA) providing batch-specific data is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and hydrolysis. The product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Phosphorus)	≥ 98% of theoretical
Solubility	Soluble in chloroform, methanol; insoluble in water
Loss on Drying	≤ 2.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.