Description

L-Ampicillin is a semi-synthetic penicillin antibiotic belonging to the aminopenicillin class, specifically the L-enantiomer of ampicillin. This compound is critical for its potent antibacterial activity, particularly against a wide range of Gram-positive and some Gram-negative bacteria. It is an essential intermediate and active pharmaceutical ingredient (API) for the research and development of novel antibiotic formulations and combination therapies. Key industries that rely on this high-purity material include pharmaceutical manufacturing, biotechnology research, and academic institutions focused on microbiology and medicinal chemistry.

Application

• Pharmaceutical API Synthesis: Serves as a key starting material or intermediate in the production of finished antibiotic dosage forms, including injectables and oral formulations.
• Microbiological Research: Used in laboratory studies to investigate bacterial resistance mechanisms, antibiotic efficacy, and the synthesis of novel β-lactam compounds.
• Reference Standard: Employed as a high-purity chemical standard in analytical laboratories for quality control (QC) and quality assurance (QA) testing of commercial ampicillin products.
• Bioconjugation & Prodrug Development: Acts as a building block for creating targeted antibiotic conjugates and prodrugs designed for enhanced delivery and reduced side effects.
• Cell Culture Applications: Utilized in selective media for biotechnology and cell culture processes to prevent bacterial contamination.

Basic Information

Product Name	L-Ampicillin
CAS No.	19379-33-0
Molecular Formula	C16H19N3O4S
Molecular Weight	349.41 g/mol
Synonyms	(2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; D-(-)-α-Aminobenzylpenicillin; Ampicillin L-Form; (S)-Ampicillin; L-(-)-Ampicillin; Ampicillin Enantiomer; NSC 528983; Antibiotic BRL 1341
EINECS	Contact for details

Quality Control

Our L-Ampicillin CAS NO 19379-33-0 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and tests for residual solvents and related substances, ensuring compliance with in-house specifications aligned with ICH guidelines. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistent quality for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Chiral Purity (HPLC)	≥ 99.0% (L-Enantiomer)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.