Description

Dimethyl 4,5-Difluorophthalate is a high-purity fluorinated aromatic ester, a key synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile, functionalized building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty polymers who require reliable, high-quality fluorinated precursors.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially those requiring a difluorinated phthalate core structure.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the introduction of fluorine atoms enhances biological activity and stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated liquid crystal compounds used in display technologies.
• Polymer & Resin Modifier: Incorporated as a monomer or additive to impart specific properties like chemical resistance or altered refractive index in specialty polymers.
• Organic Synthesis & Research: A versatile reagent in academic and industrial R&D labs for constructing complex aromatic and heterocyclic systems.
• Dye & Pigment Intermediate: Used in the synthesis of specialized fluorinated dyes and pigments.

Basic Information

Product Name	Dimethyl 4,5-Difluorophthalate
CAS No.	18959-32-5
Molecular Formula	C10H8F2O4
Molecular Weight	230.17 g/mol
Synonyms	4,5-Difluorophthalic Acid Dimethyl Ester; Dimethyl 4,5-Difluorobenzene-1,2-dicarboxylate; 1,2-Benzenedicarboxylic Acid, 4,5-Difluoro-, Dimethyl Ester; Phthalic Acid, 4,5-Difluoro-, Dimethyl Ester; 4,5-Difluorophthalic Acid, Dimethyl Ester; Methyl 4,5-Difluorophthalate; 4,5-DFPA Dimethyl Ester
EINECS	Contact for details

Quality Control

Our Dimethyl 4,5-Difluorophthalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is moisture-sensitive; ensure containers are sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.