Description

o-Fluorocinnamic Acid is a versatile fluorinated aromatic building block characterized by its cinnamic acid backbone with an ortho-fluorine substituent. This specific substitution pattern is crucial for fine-tuning the electronic and steric properties of target molecules in advanced synthesis. It serves as a key intermediate for researchers and manufacturers in the pharmaceutical and agrochemical sectors, enabling the development of novel active compounds. Its utility extends to material science for creating specialized polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A critical synthon for the research and development of fluorinated drug candidates, including potential kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides and herbicides, where the fluorine atom can enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic semiconductors and liquid crystal molecules used in display technologies.
• Polymer Modification: Incorporated into polymer chains to impart specific properties like altered solubility, thermal stability, or optical characteristics.
• Chemical Research & Development: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new fluorination methodologies.
• Fluorescent Probe & Dye Synthesis: Acts as a starting material for synthesizing fluorophores and molecular probes used in bioimaging and diagnostics.

Basic Information

Product Name	o-Fluorocinnamic Acid
CAS No.	18944-77-9
Molecular Formula	C9H7FO2
Molecular Weight	166.15 g/mol
Synonyms	(2-Fluorophenyl)acrylic acid; 2-Fluorocinnamic acid; (E)-3-(2-Fluorophenyl)acrylic acid; (2-Fluorobenzene)acrylic acid; trans-2-Fluorocinnamic acid; ortho-Fluorocinnamic Acid; 3-(2-Fluorophenyl)-2-propenoic acid
EINECS	242-714-4

Quality Control

Our o-Fluorocinnamic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 147 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.